Oxford University researchers behind the landmark study said it offered the 'first glimmer of hope' in the battle to find a drug that slows or stops the development of Alzheimer's.
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The breakthrough centres on a compound called homocysteine which is naturally made in the body and, at high levels, has been linked to memory loss and Alzheimer's.
Vitamin B is known to break down homocysteine, so the researchers decided to look at whether giving patients the vitamin would be good for memory.
The tablets contained extremely high doses of vitamins B6, 9 and 12.
For instance, the amount of B12 was up to 300 times higher than could be obtained by simply eating bananas, meat, wholegrains, beans and other foods rich in the vitamin.
A simple vitamin pill could prevent millions from suffering the agony of Alzheimer's.