If you are unsure of how to react to particularly loud whisper or a nasty comment, take your cue from your partner.
If you have chosen a public place like a movie theater or restaurant, prepare yourself mentally for negative reactions from some people around.
If he/she is ready to date, in all likelihood he/she knows well enough to manage their condition too.
Thus don’t be fussy or extra-solicitous towards your date.
Don’t go out with someone in a wheelchair under the mistaken impression that he/she needs to be cared, cheered up or looked after.
At the same time though, be aware that they may need some assistance during the date.